Abstract: The proper management of demolition construction waste from the construction industry is an issue that has gained relevance over the last years in several research centers around the world and, in this context, researches on the potential of using construction and demolition waste to execute pavement layers have been stood out. The paper presented results of a research performed to evaluate the characteristics of the material produced by a waste treatment/beneficiation industrial plant. Tests to verify the suitability of the material as pavement subbase material were performed according Brazilian code - grain-size distribution composition, maximum characteristic dimension, shape particle index (SPI), contaminant percentage and sieving process. The results obtained indicated that the recycled aggregates investigated performed well in all the requirements of the reference standards used and only one correction, related to grain size distribution, was performed using a sieving process. It is important to highlight that the tests and analyses must be performed constantly when forming each aggregate batch, since the recycled aggregates are usually quite heterogeneous, with characteristics that may vary depending on the type of work, construction materials used or period of the year.

The selective serotonin reuptake inhibitor fluoxetine (FLX) is widely prescribed for depression and anxiety-related disorders. On the other hand, enhanced serotonergic transmission is known to be classically related to anxiety. In this study, the effects of acute (5.0 mg/kg) and chronic (5.0 mg/kg, 22 days) FLX were investigated in both food-deprived and non-deprived rats tested in the elevated plus-maze. Significant main effects of the three factors (drug, food condition and administration regimen) were observed, but no interaction between them. The administration of either acute or chronic FLX resulted in an anxiogenic effect, as detected by a significant reduction in the percentage of time spent in the open arms and in the percentage of open arm entries. Food deprivation yielded an anxiolytic-like profile, probably related to changes in locomotor activity. The administration regimen resulted in an anxiolytic profile in chronically treated rats, as would be expected after 22 days of regular handling. The anxiogenic action of acute FLX is consistent with both its neurochemical and clinical profile. The discrepancy between the anxiogenic profile of chronic FLX and its therapeutic uses is discussed in terms of possible differences between the type of anxiety that is measured in the plus-maze and the types of human anxiety that are alleviated by fluoxetine.